2′-Hydroxy-2,3-dimethoxychalcone
α-Gracinoic acid is a Chalcone (HY-121054) derivative with anti-inflammatory activity. α-Gracinoic acid inhibits nitric oxide production catalyzed by inducible nitric oxide synthase (iNOS) in lipopolysaccharide (LPS)-treated RAW 264.7 cells.
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- CAS No.: 42220-80-4
- 화학식: C17H16O4
- 분자량:284.31
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A2780cisR | GI50 |
14.38 μM
Compound: 4
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Growth inhibition of cisplatin-resistant human A2780cis cells after 7 days by crystal violet staining based clonogenic assay
Growth inhibition of cisplatin-resistant human A2780cis cells after 7 days by crystal violet staining based clonogenic assay
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[PMID: 24565968] |
| RAW264.7 | IC50 |
3.8 μM
Compound: 15
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Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by enzyme immunoassay
Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by enzyme immunoassay
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[PMID: 19233646] |
Chemical Information
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CAS No. 42220-80-4
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분자량 284.31
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화학식 C17H16O4
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SMILES
O=C(C1=C(O)C=CC=C1)/C=C/C2=C(OC)C(OC)=CC=C2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2′-Hydroxy-2,3-dimethoxychalcone Related Classifications
HY-164361 Related Classifications
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