Nitromifene
Nitromifene is an antagonist of estrogen receptor (ER).
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- CAS No.: 10448-84-7
- 화학식: C27H28N2O4
- 분자량:444.52
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
IC50 & Target
ER[1]
In Vitro
Nitromifene is an antagonist of estrogen receptor (ER). At 0.5 μM and 1.0 μM concentrations, Nitromifene inhibits MCF 7 cell proliferation to 70% of that in drug-free controls. At higher concentrations, Nitromifene is clearly more effective than other metabolites. Specifically bound estradiol is displaced from intact MCF 7 cells by Nitromifene. Nitromifene is an effective antagonist of the ability of calmodulin (CM) to activate cyclic nucleotide phosphodiesterase[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 10448-84-7
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분자량 444.52
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화학식 C27H28N2O4
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SMILES
O=[N+](/C(C1=CC=CC=C1)=C(C2=CC=C(OCCN3CCCC3)C=C2)/C4=CC=C(OC)C=C4)[O-]
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Synonyms
CI-628
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nitromifene Related Classifications
HY-100266 Related Classifications
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