AChE-IN-28
AChE-IN-28 (Compound 2h) is a selective slow-binding inhibitor of acetylcholinesterase with an IC50 of 0.2 nM.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C33H48BrF3N5O4
- 분자량:715.66
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- 순도&문서
- References
-
Help & FAQs
Biological Activity
|
AChE 0.2 nM (IC50) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Female Wistar rats, experimental autoimmune model of myasthenia gravis (EAMG)[1]
-
Dosage:0.005, 0.01, 0.015 and 0.1 mg/kg
-
Administration:Intraperitoneal injection, single dose
-
Result:The dose that restored the value of decrement of amplitude of APs in animals with EAMG to the level of control rats was 0.01 mg/kg. Showed a long lasting effect and had no significant effect on the force of urinary bladder contractions in animals with EAMG.
Chemical Information
-
분자량 715.66
-
화학식 C33H48BrF3N5O4
-
SMILES
CC[N+](CCCCCN1C(C=CN(C1=O)CCCCCCN(C(C=C2=O)C)C(N2C)=O)=O)(CC3=CC=CC=C3C(F)(F)F)CC.[Br-]
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AChE-IN-28 Related Classifications
HY-151927 Related Classifications
Powered by Bioz