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Cat. No.: HY-144324

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AChE-IN-6

AChE-IN-6 (Compound 12a) is an optimal multifunctional ligand with significant inhibition of AChE (EeAChE, IC₅₀ = 0.20 μM; HuAChE, IC₅₀ = 37.02 nM) and anti-Aβ activity (IC₅₀ = 1.92 μM for self-induced Aβ1-42 aggregation; IC₅₀ = 1.80 μM for disaggregation of Aβ1-42 fibrils; IC₅₀ = 2.18 μM for Cu2+-induced Aβ1-42 aggregation; IC₅₀ = 1.17 μM for disaggregation of Cu2+-induced Aβ1-42 fibrils). AChE-IN-6 has the potential for the research of Alzheimer's disease.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2758788-95-1
화학식: C₂₉H₄₁N₅O₂
분자량:491.67

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

AChE-IN-6 Chemical Structure

CAS No.: 2758788-95-1

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All Cholinesterase (ChE) Isoforms :

AChE
BChE

Chemical Information

CAS No. 2758788-95-1
분자량 491.67
화학식 C₂₉H₄₁N₅O₂
SMILES

CCN(CC1=C(C=CC=C1)N(C)C)CCCCCCN2N=C(C=CC2=O)C3=CC(N(C)C)=CC=C3O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Shi Y, et al. Development of novel 2-aminoalkyl-6-(2-hydroxyphenyl)pyridazin-3(2H)-one derivatives as balanced multifunctional agents against Alzheimer's disease. Eur J Med Chem. 2022;230:114098. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

AChE-IN-6

All Cholinesterase (ChE) Isoforms

Biological Activity

제품 설명

Chemical Information

순도&문서

References

Calculators

Help & FAQs

AChE-IN-6 Related Classifications

HY-144324 Related Classifications

Bioz

Keywords

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