AFG206
AFG206 is a first-generation ATP competitive “type II” FLT3 inhibitor. AFG206 potently inhibits cell proliferation (IC50 around 0.1 µM) via induction of Apoptosis in FLT3-ITD-Ba/F3 cells and D835Y-Ba/F3 cells. AFG206 is promising for research of acute myeloid leukemia.
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- CAS No.: 630122-37-1
- 화학식: C20H19N3O2
- 분자량:333.38
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 630122-37-1
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분자량 333.38
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화학식 C20H19N3O2
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SMILES
O=C(NC1=CC=C(CC)C=C1)NC2=CC=C(C=C2)OC3=CC=NC=C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)