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Cat. No.: HY-122007

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AM-0561

Name: AM-0561
Brand: MedChemExpress
SKU: HY-122007
Availability: PreOrder

1 Cited Publications

고객리뷰

Based on 1 publication(s) in Google Scholar

AM-0561 is a NIK inhibitor (K_i: 0.3 nM). AM-0561 decreases p52 levels.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1202764-63-3
화학식: C₁₈H₁₃ClN₆OS
분자량:396.85

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

AM-0561 Chemical Structure

CAS No.: 1202764-63-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

AM-0561 is a NIK inhibitor (K_i: 0.3 nM). AM-0561 decreases p52 levels^[1].

All NF-κB Isoforms :

Chemical Information

CAS No. 1202764-63-3
분자량 396.85
화학식 C₁₈H₁₃ClN₆OS
SMILES

C[C@](C1=NC=CS1)(C#CC2=CN3C(C4=NC(N)=NC=C4Cl)=CN=C3C=C2)O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Journal Impact Factor

NPJ Precis Oncol

Integrative profiling strategies to guide personalized therapy in mantle cell lymphoma: a pilot study. [Abstract]

2025 Nov 21;9(1):373. PMID: 41272086

순도&문서

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Demchenko YN, et al. Novel inhibitors are cytotoxic for myeloma cells with NFkB inducing kinase-dependent activation of NFkB. Oncotarget. 2014 Jun 30;5(12):4554-66. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Publications (1)
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AM-0561

Publications Citing Use of MedChemExpress (MCE) AM-0561

All NF-κB Isoforms

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Publications (1)

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AM-0561

Publications Citing Use of MedChemExpress (MCE) AM-0561

All NF-κB Isoforms

Biological Activity

제품 설명

Chemical Information

Publications (1)

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