Antibacterial agent 294
Antibacterial agent 294 is an antibacterial agent. Antibacterial agent 294 shows antibacterial effect against carbapenem-resistant Acinetobacter baumannii (CRAB) with a MIC of 0.5 μg/mL. Antibacterial agent 294 can be used for the research of infection.
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- 화학식: C16H11N5O6
- 분자량:369.29
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
In Vitro
Antibacterial agent 294 (Compound 7l) (48 h) shows no significant cytotoxicity in Vero cells and NIH-3T3 cells with CC50 values >200 μg/mL[1].
Antibacterial agent 294 (1-2 μg/mL) exhibits potent inhibitory activity against multiple clinical isolates of multidrug-resistant Acinetobacter baumannii (MDR-AB), with an MIC range of 1-2 μg/mL and has a MIC value of 1 μg/mL for the standard strain ATCC-17978[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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분자량 369.29
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화학식 C16H11N5O6
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SMILES
O=C(NNC1=CC=C([N+]([O-])=O)C=C1)C2=NOC(C3=CC([N+]([O-])=O)=CC=C3)=C2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocol
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antibacterial agent 294 Related Classifications
HY-178384 Related Classifications
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