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Cat. No.: HY-182718

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AZD0011-PL

AZD0011-PL is a human arginase 1/ 2 inhibitor with IC₅₀ values of 0.01 μM and 0.02 μM. AZD0011-PL can be used for the researches of cancer, respiratory inflammatory disease.

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CAS No.: 2374807-39-1
화학식: C₉H₁₉BN₂O₄
분자량:230.07

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

AZD0011-PL Chemical Structure

CAS No.: 2374807-39-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

AZD0011-PL is a human arginase 1/ 2 inhibitor with IC₅₀ values of 0.01 μM and 0.02 μM. AZD0011-PL can be used for the researches of cancer, respiratory inflammatory disease^[1].

IC₅₀ & Target^[1]

hArginase 1

0.01 μM (IC₅₀)

hArginase 2

0.02 μM (IC₅₀)

In Vitro

AZD0011-PL (Compound 7) potently inhibits recombinant human Arginase 1 with an IC₅₀ of 0.01 μM and recombinant human Arginase 2 with an IC₅₀ of 0.02 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2374807-39-1
분자량 230.07
화학식 C₉H₁₉BN₂O₄
SMILES

OB(O)CCCC[C@]1(NC[C@@H](C1)N)C(O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Scott Nathan MLYNARSKI, et al. Arginase inhibitors and methods of use thereof. WO2019159120A1. 2020-08-17

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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