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Cat. No.: HY-13862S

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AZD1080-d₈

AZD1080-d₈ is the deuterium labeled AZD1080 (HY-13862). AZD1080 is a potent and selective GSK3 inhibitor. AZD1080 inhibits recombinant human GSK3α and GSK3β with pK_i (IC₅₀) of 8.2 (6.9 nM) and 7.5 (31 nM), respectively.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₁₉H₁₀D₈N₄O₂
분자량:342.42

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

AZD1080-d₈ Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
- 신청
Chemical Information
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Biological Activity

제품 설명

All GSK-3 Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

신청

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled CAS 612487-72-6
분자량 342.42
화학식 C₁₉H₁₀D₈N₄O₂
SMILES

OC(N1)=C(C2=CC=C(CN3C([2H])([2H])C([2H])([2H])OC([2H])([2H])C3([2H])[2H])C=N2)C4=C1C=CC(C#N)=C4
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.