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Cat. No.: HY-184704

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BChE-IN-52

BChE-IN-52 is a selective butyrylcholinesterase (BChE) inhibitor with an IC₅₀ of 0.25 μM against horse serum-derived BChE. BChE-IN-52 exhibits weak antioxidant activity, shows no mutagenicity, and displays photochemical instability under UV irradiation. BChE-IN-52 can be used in the research of Alzheimer's disease.

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화학식: C₂₀H₁₈N₂O₃S
분자량:366.43

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

BChE-IN-52 Chemical Structure

사이즈

가격

재고

수량

Amount: USD 0.00

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

BChE

0.25 μM (IC₅₀)

All Cholinesterase (ChE) Isoforms :

AChE
BChE

In Vitro

BChE-IN-52 (Compound 14) (30 min) exhibits weak copper-reducing antioxidant activity with a capacity of 0.05 mol TE/mol^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

분자량 366.43
화학식 C₂₀H₁₈N₂O₃S
SMILES

O=C(N1CCCC1)OC2=CC=CC=C2/C=C/C3=CC=C(C4=CN=CO4)S3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Mlakić M, et al. Novel resveratrol-inspired thieno-benzimidazoles and thieno-oxazoles - Synthesis, selective butyrylcholinesterase inhibition and molecular modeling. Bioorganic chemistry. 2026 Jun 17;180:110096. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

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BChE-IN-52

All Cholinesterase (ChE) Isoforms