Bicalutamide-d4
Bicalutamide-d4 is the deuterium labeled Bicalutamide. Bicalutamide is an orally active non-steroidal androgen receptor (AR) antagonist. Bicalutamide can be used for the research of prostate cancer.
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- CAS No.: 1185035-71-5
- 화학식: C18H10D4F4N2O4S
- 분자량:434.40
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
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HY-N0475
TriptophenolideAndrogen Receptor Antagonist -
HY-14248S
Letrozole-d4Stable Isotope -
HY-70002S
DeutenzalutamideAndrogen Receptor Antagonist -
HY-B1986
p,p'-DDEAndrogen Receptor Antagonist -
HY-N0437S
Progesterone-d9Stable Isotope -
HY-N7045
Isosilybin BNatural Product -
HY-109619
D4-abirateroneAbiraterone Metabolite -
HY-N0475R
Triptophenolide (Standard)Androgen Receptor Antagonist -
HY-B0412S
Estriol-d2Stable Isotope -
HY-B0234S1
Estrone-d2Stable Isotope -
HY-122025
AC-262536Androgen Receptor Agonist -
HY-113405S1
21-Deoxycortisol-d8Stable Isotope
Biological Activity
제품 설명
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
신청
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1185035-71-5
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Unlabeled CAS 90357-06-5
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Appearance Solid
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분자량 434.40
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화학식 C18H10D4F4N2O4S
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Color White to off-white
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SMILES
O=C(NC1=CC=C(C#N)C(C(F)(F)F)=C1)C(C)(O)CS(=O)(C2=C([2H])C([2H])=C(F)C([2H])=C2[2H])=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Protocol
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Research Protocol for Endocrine Diseases
Endocrine diseases often arise from disrupted hormone production, hormone signaling, or target-tissue responsiveness; for diabetes-focused endocrine disease models, insulin signaling regulates glucose uptake, hepatic glucose output, lipid metabolism, and β-cell compensation. Type 2 diabetes develops through interacting defects in insulin resistance, β-cell dysfunction, adipose inflammation, hepatic glucose overproduction, altered incretin signaling, and ectopic lipid metabolism. A major unresolved question is whether endocrine dysfunction is driven primarily by target-tissue insulin resistance, intrinsic β-cell failure, immune/inflammatory stress, or combined multi-organ failure that differs by disease stage.
순도&문서
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Data Sheet (269 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Bicalutamide-d4 Related Classifications
HY-14249S Related Classifications
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