CAR-2
CAR-2 is a BODIPY-based photosensitizer that induces ferroptosis in photodynamic therapy (PDT) by targeting the endoplasmic reticulum (ER) and lipid droplets (LDs). CAR-2 exhibits phototoxicity in breast cancer cells with IC50 of 0.01-0.02 μM. CAR-2 exhibits antitumor efficacy in 4T1 xenograft mouse models.
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- CAS No.: 3030055-40-1
- 화학식: C27H23BF2I2N4O2
- 분자량:738.11
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
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Help & FAQs
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 3030055-40-1
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분자량 738.11
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화학식 C27H23BF2I2N4O2
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SMILES
O=C(C1=CC2=C(N(C3=CC=CC=C32)C)C(C4=C5[N+]([B-](F)(N6C4=C(C(I)=C6C)C)F)=C(C(I)=C5C)C)=N1)OC
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CAR-2 Related Classifications
HY-D2620 Related Classifications
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