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Cat. No.: HY-121545

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CB-52

Name: CB-52
Brand: MedChemExpress
SKU: HY-121545
Price: 70.00 USD
Availability: InStock
Rating: 5 (1 reviews)

CB-52 is the ligand and neutral antagonist of CB2 cannabinoid receptor.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 869376-90-9
화학식: C₂₆H₄₃NO₃
분자량:417.62

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

CB-52 Chemical Structure

CAS No.: 869376-90-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
- In Vitro
- In Vivo
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

CB-52 is the ligand and neutral antagonist of CB2 cannabinoid receptor^[1].

All Cannabinoid Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
RBL-2H3	IC₅₀	13 μM Compound: 52	Inhibition of anandamide membrane transporter in RBL-2H3 cells assessed as [14C]anandamide uptake Inhibition of anandamide membrane transporter in RBL-2H3 cells assessed as [14C]anandamide uptake	[PMID: 16279794]

In Vitro

CB-52 inhibits Forskolin (HY-15371)-induced cAMP formation by N18TG2 cells (IC₅₀: 450 nM) and hCB1-CHO cells (EC₅₀: 2600 nM)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

CB-52 (1 and 5 mg/kg, i.p.) decreases pain threshold to thermal stimulation in rats, and blocks WIN55,212-2 (2.5 mg/kg, i.p.) caused anti-nociceptive effect^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 869376-90-9
분자량 417.62
화학식 C₂₆H₄₃NO₃
SMILES

O=C(CCCCCCCCCCOC1=CC(O)=CC=C1CCCCCC)NC2CC2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Cascio MG, et al. In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands. Br J Pharmacol. 2006 Oct;149(4):431-40. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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