CHBO4
CHBO4 is a potent, reversible, competitive, and selective hMAO-B inhibitor with an IC50 value of 0.031 μM in CHBO subseries and an Ki value of 0.010 ± 0.005 μM. CHBO4 reduce cell damage by scavenging intracellular reactive oxygen species (ROS). CHBO4 can be used for Parkinson's Disease (PD) research.
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- CAS No.: 98991-32-3
- 화학식: C15H10BrFO
- 분자량:305.14
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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hMAO-B 0.031 μM (IC50) |
hMAO-B 0.010 μM (Ki) |
CHBO4 (10-500 µg/mL, 48 h) is biologically safe in Vero cells[1].
CHBO4 (128.8 µg/mL, 10 min) can reduce ROS generation in Vero cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Vero cells
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Concentration:10-500 µg/mL
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Incubation Time:48 h
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Result:Reduced cell viability percentage with the IC50 value of 128.8 µg/mL
Decreased cellular density, cellular shrinkage, and blebbing exposed to concentrations (100-300 µg/mL) in Vero cells
Chemical Information
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CAS No. 98991-32-3
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분자량 305.14
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화학식 C15H10BrFO
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SMILES
BrC1=CC=C(C(/C=C/C2=CC=C(F)C=C2)=O)C=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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