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Cat. No.: HY-177073

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Cleminorexton

Name: Cleminorexton
Brand: MedChemExpress
SKU: HY-177073
Price: 1340.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Cleminorexton is an orally active orexin-2 receptor (OX2R) agonist with a pEC₅₀ between 9 and 10.4. Cleminorexton can be used for narcolepsy and other conditions associated with orexin deficiency and/or excessive sleepiness.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2980518-93-0
화학식: C₂₄H₂₄F₄N₂O₄S
분자량:512.52

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Cleminorexton Chemical Structure

CAS No.: 2980518-93-0

사이즈

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All Orexin Receptor (OX Receptor) Isoforms :

In Vivo

Cleminorexton (Compound 67A/Example 47) (1-10 mg/kg, p.o., single dose) shows significant arousal-promoting activity in mouse models^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2980518-93-0
분자량 512.52
화학식 C₂₄H₂₄F₄N₂O₄S
SMILES

FC1=C(C2=C(C(F)=CC(F)=C2)OCCC3=O)C=CC=C1C[C@]4([H])N3CCC[C@@]4(NS(C5(CC5)F)(=O)=O)[H]
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gregory R. Ott, et al., Medium- or macro-cyclic benzyl-substituted heterocycle derivatives and related uses. WO2023167925A1.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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