Copper tripeptide
Based on 1 publication(s) in Google Scholar
Copper tripeptide (GHK-Cu) is a tripeptide. During wound healing, Copper tripeptide may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide is a natural modulator of multiple cllular pathways in skin regeneration.
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- Purity: 99.92%
- CAS No.: 89030-95-5
- 화학식: C14H22CuN6O4
- 분자량:401.91
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보관:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Copper tripeptide
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Biological Activity
Copper tripeptide (1 nM; 0-96 hours) affects irradiated fibroblasts such that their population-doubling times approximated that of controls[1]. Copper tripeptide (1 nM; 0-120 hours) significantly produces more basic fibroblast growth factors than normal controls at a 24-hour interval of irradiated fibroblasts[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 89030-95-5
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Appearance Solid
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분자량 401.91
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화학식 C14H22CuN6O4
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Color Blue to purple
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Synonyms
GHK-Cu
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Sequence
Gly-His-Lys-Cu
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Sequence Shortening
GHK-Cu
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
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Journal Impact Factor
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Most Recent
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J Appl Toxicol
Copper induces oxidative stress and apoptosis of hippocampal neuron via pCREB/BDNF/ and Nrf2/HO-1/NQO1 pathway. [Abstract]2022 Apr;42(4):694-705. PMID: 34676557
용액&용해도
H2O : 50 mg/mL (124.41 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (274 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.4881 mL | 12.4406 mL | 24.8812 mL | 62.2030 mL |
| 5 mM | 0.4976 mL | 2.4881 mL | 4.9762 mL | 12.4406 mL | |
| 10 mM | 0.2488 mL | 1.2441 mL | 2.4881 mL | 6.2203 mL | |
| 15 mM | 0.1659 mL | 0.8294 mL | 1.6587 mL | 4.1469 mL | |
| 20 mM | 0.1244 mL | 0.6220 mL | 1.2441 mL | 3.1101 mL | |
| 25 mM | 0.0995 mL | 0.4976 mL | 0.9952 mL | 2.4881 mL | |
| 30 mM | 0.0829 mL | 0.4147 mL | 0.8294 mL | 2.0734 mL | |
| 40 mM | 0.0622 mL | 0.3110 mL | 0.6220 mL | 1.5551 mL | |
| 50 mM | 0.0498 mL | 0.2488 mL | 0.4976 mL | 1.2441 mL | |
| 60 mM | 0.0415 mL | 0.2073 mL | 0.4147 mL | 1.0367 mL | |
| 80 mM | 0.0311 mL | 0.1555 mL | 0.3110 mL | 0.7775 mL | |
| 100 mM | 0.0249 mL | 0.1244 mL | 0.2488 mL | 0.6220 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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