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Cat. No.: HY-161889

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DCSM06-05

DCSM06-05 is a potent SMARCA2-BRD inhibitor with an IC₅₀ value of 9 µM, a K_d value of 22.4 µM.

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CAS No.: 880811-10-9
화학식: C₂₁H₂₁FN₂O₂
분자량:352.40

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

DCSM06-05 Chemical Structure

CAS No.: 880811-10-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

DCSM06-05 is a potent SMARCA2-BRD inhibitor with an IC₅₀ value of 9 µM, a K_d value of 22.4 µM^[1].

IC₅₀ & Target^[1]

Brd

9 μM (IC₅₀)

All SWI/SNF Complex Isoforms :

Chemical Information

CAS No. 880811-10-9
분자량 352.40
화학식 C₂₁H₂₁FN₂O₂
SMILES

COC1=CC(CNCC2=CC=CC=N2)=CC=C1OCC3=C(F)C=CC=C3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lu T, et al. Identification of small molecule inhibitors targeting the SMARCA2 bromodomain from a high-throughput screening assay. Acta Pharmacol Sin. 2018 Sep;39(9):1544-1552. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

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DCSM06-05

All SWI/SNF Complex Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

DCSM06-05 Related Classifications

HY-161889 Related Classifications