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Cat. No.: HY-N3711

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Dehydrocrenatine

Dehydrocrenatidine, a β-carboline alkaloid that can be isolated from Picrasma quassioides. Dehydrocrenatidine induces cell apoptosis by activates ERK and JNK. Dehydrocrenatidine inhibits invasion and migration of cancer cells, it also suppresses neuronal excitability to exert analgesic effects.

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CAS No.: 26585-13-7
화학식: C₁₄H₁₂N₂O
분자량:224.26

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Dehydrocrenatine Chemical Structure

CAS No.: 26585-13-7

사이즈

가격

재고

수량

Amount: USD 0.00

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All JNK Isoforms :

All ERK Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
A2780	IC₅₀	4.77 μg/mL Compound: 50	Antiproliferative activity against human A2780 cells Antiproliferative activity against human A2780 cells	[PMID: 34332400]
SK-OV-3	IC₅₀	15.72 μg/mL Compound: 50	Antiproliferative activity against human SK-OV-3 cells Antiproliferative activity against human SK-OV-3 cells	[PMID: 34332400]

Chemical Information

CAS No. 26585-13-7
분자량 224.26
화학식 C₁₄H₁₂N₂O
SMILES

COC1=CN=C(C=C)C(N2)=C1C3=C2C=CC=C3
Structure Classification
- Alkaloids
- Indole Alkaloids
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ho HY, et al. Apoptotic effects of dehydrocrenatidine via JNK and ERK pathway regulation in oral squamous cell carcinoma. Biomed Pharmacother. 2021 May;137:111362. [Content Brief]

[2]. Hsieh MC, et al. Dehydrocrenatidine extracted from Picrasma quassioidesinduces the apoptosis of nasopharyngeal carcinoma cells through the JNK and ERK signaling pathways. Oncol Rep. 2021 Aug;46(2):166. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
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Dehydrocrenatine

All JNK Isoforms

All ERK Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Dehydrocrenatine Related Classifications

HY-N3711 Related Classifications