Dithiazanine iodide
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Dithiazanine iodide is a broad-spectrum anthelmintic that induces irreversible relaxation and death of Trichuris trichiura. Dithiazanine iodide is used in research related to trichuriasis, strongyloidiasis, ascariasis, enterobiasis and hookworm infections.
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- Purity: 99.46%
- CAS No.: 514-73-8
- 화학식: C23H23IN2S2
- 분자량:518.48
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보관:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
All Parasite Isoforms
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Biological Activity
Chemical Information
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CAS No. 514-73-8
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Appearance Solid
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분자량 518.48
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화학식 C23H23IN2S2
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Color Green to dark green
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SMILES
CCN1/C(SC2=CC=CC=C12)=C\C=C\C=C\C3=[N+](CC)C4=CC=CC=C4S3.[I-]
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
용액&용해도
DMSO : 16.67 mg/mL (32.15 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (282 KB)
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SDS (421 KB)
- English - EN (421 KB)
- Français - FR (421 KB)
- Deutsch - DE (421 KB)
- Norwegian - NO (421 KB)
- Español - ES (421 KB)
- Swedish - SV (421 KB)
- Italian - IT (421 KB)
- Korean - KR (421 KB)
- Portuguese - PT (421 KB)
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Handling Instructions (2659 KB)
References
[1]. SWARTZWELDER JC, et al. Dithiazanine, an effective broad-spectrum anthelmintic; results of therapy of trichuriasis, strongyloidiasis, enterobiasis, ascariasis, and hookworm infection. J Am Med Assoc. 1957 Dec 21;165(16):2063-7. [Content Brief]
[2]. ABADIE SH, et al. A FATALITY ASSOCIATED WITH DITHIAZANINE IODIDE THERAPY. JAMA. 1965 Apr 26;192:326-7. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9287 mL | 9.6436 mL | 19.2871 mL | 48.2179 mL |
| 5 mM | 0.3857 mL | 1.9287 mL | 3.8574 mL | 9.6436 mL | |
| 10 mM | 0.1929 mL | 0.9644 mL | 1.9287 mL | 4.8218 mL | |
| 15 mM | 0.1286 mL | 0.6429 mL | 1.2858 mL | 3.2145 mL | |
| 20 mM | 0.0964 mL | 0.4822 mL | 0.9644 mL | 2.4109 mL | |
| 25 mM | 0.0771 mL | 0.3857 mL | 0.7715 mL | 1.9287 mL | |
| 30 mM | 0.0643 mL | 0.3215 mL | 0.6429 mL | 1.6073 mL |