FCH-2296413
Based on 1 Customer Validation
FCH-2296413 is a potent and selective hydroxycarboxylic acid receptor (HCAR) agonist with an EC50 of 4.4-8.6 nM. FCH-2296413 exhibits analgesic activity and can be used for the research of peripheral pain-related diseases.
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- Purity: 96.37%
- CAS No.: 1229028-63-0
- 화학식: C8H8N6
- 분자량:188.19
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보관:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | EC50 |
0.21 μM
Compound: (+/-)17a
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Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay
Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay
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[PMID: 20363624] |
Chemical Information
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CAS No. 1229028-63-0
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Appearance Solid
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분자량 188.19
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화학식 C8H8N6
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Color Light yellow to light brown
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SMILES
C1(C2=NNC3=C2CC4CC34)=NN=NN1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
용액&용해도
DMSO : 15 mg/mL (79.71 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.3138 mL | 26.5689 mL | 53.1378 mL | 132.8445 mL |
| 5 mM | 1.0628 mL | 5.3138 mL | 10.6276 mL | 26.5689 mL | |
| 10 mM | 0.5314 mL | 2.6569 mL | 5.3138 mL | 13.2844 mL | |
| 15 mM | 0.3543 mL | 1.7713 mL | 3.5425 mL | 8.8563 mL | |
| 20 mM | 0.2657 mL | 1.3284 mL | 2.6569 mL | 6.6422 mL | |
| 25 mM | 0.2126 mL | 1.0628 mL | 2.1255 mL | 5.3138 mL | |
| 30 mM | 0.1771 mL | 0.8856 mL | 1.7713 mL | 4.4281 mL | |
| 40 mM | 0.1328 mL | 0.6642 mL | 1.3284 mL | 3.3211 mL | |
| 50 mM | 0.1063 mL | 0.5314 mL | 1.0628 mL | 2.6569 mL | |
| 60 mM | 0.0886 mL | 0.4428 mL | 0.8856 mL | 2.2141 mL |
FCH-2296413 Related Classifications
HY-403593 Related Classifications
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