FeTPPS
Based on 1 publication(s) in Google Scholar
FeTPPS, a 5,10,15,20-tetrakis (4-sulfonatophenyl) porphyrin iron III chloride peroxynitrite decomposition catalyst, possesses evident neuroprotective effects in a experimental model of spinal cord damage. FeTPPS acts as a peroxynitrite scavenger and anti-nitrating agent in vivo. FeTPPS reduces nitric oxide (NO) production and apoptosis process.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.9%
- CAS No.: 90384-82-0
- 화학식: C44H28ClFeN4O12S4
- 분자량:1024.27
-
보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
용액&용해도
- 순도&문서
- References
-
Help & FAQs
-
HY-18729A
L-NAME hydrochloride
-
HY-148439
Daraxonrasib
-
HY-136278
DETA NONOate
-
HY-K0010
Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO)
-
HY-18731
1400W Dihydrochloride
-
HY-120380
FeTMPyP
-
HY-D1148
HKGreen-4I
-
HY-D0187
L-Glutathione reduced
-
HY-D0187R
L-Glutathione reduced (Standard)
-
HY-18732A
L-NMMA acetate
-
HY-134216
MAHMA NONOate
-
HY-120990
Piloty's acid
Publications Citing Use of MedChemExpress (MCE) FeTPPS
More
Biological Activity
FeTPPS acts as an effective pro-oxidant towards appreciable substrates in vitro in the presence of oxidant. FeTPPS protects cells against oxidative damage induced by H2O2, generated by Glucose (G)-glucose oxidase (GO) system[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:Human hepatocellular carcinoma (HepG2)
-
Concentration:5, 10, 15, 20, 25 μM
-
Incubation Time:Treated 12 h before being exposed to H2O2
-
Result:Could protect cells against oxidative damage induced by H2O2.
Chemical Information
-
CAS No. 90384-82-0
-
Appearance Solid
-
분자량 1024.27
-
화학식 C44H28ClFeN4O12S4
-
Color Brown to black
-
SMILES
O=S([O-])(C1=CC=C(C(C(C=C2)=[N]3C2=C(C4=CC=C5C(C6=CC=C(S(=O)([O-])=O)C=C6)=C7C=C8)C9=CC=C(S(=O)([O-])=O)C=C9)=C%10C=CC%11=C(C%12=CC=C(S(=O)([O-])=O)C=C%12)C8=[N]7[Fe+3]3([Cl-])([N-]45)[N-]%10%11)C=C1)=O.[4H+]
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
-
Journal Impact Factor
-
Most Recent
용액&용해도
H2O : 5 mg/mL (4.88 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
-
Data Sheet (282 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
[1]. Giuseppe Bruschetta, et al. FeTPPS Reduces Secondary Damage and Improves Neurobehavioral Functions after Traumatic Brain Injury.Front Neurosci. 2017 Feb 7;11:6. [Content Brief]
[2]. Pengfei Zhang, et al. Study on the detoxification mechanisms to 5,10,15,20-tetrakis (4-sulfonatophenyl) porphyrinato iron(III) chloride (FeTPPS), an efficient pro-oxidant of heme water-soluble analogue. J Inorg Biochem. 2018 Dec;189:40-52. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.9763 mL | 4.8815 mL | 9.7631 mL | 24.4076 mL |
FeTPPS Related Classifications
HY-131697 Related Classifications
Powered by Bioz