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Product Name	Size / Unit Price	Qty

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Cat. No.: HY-P992354

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FPA154

(Synonyms: INBRX-110)

1 Cited Publications

고객리뷰

Based on 1 publication(s) in Google Scholar

FPA154 is a human monoclonal antibody against TNFRSF18/GITR/CD357. FPA154 activates NF-κB via the GITR pathway. FPA154 can be used in solid tumor research. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

FPA154 Chemical Structure

사이즈

가격

재고

수량

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* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- IC₅₀ & Target
- In Vitro
- Gene ID
- Accession
- Target
- Conjugated
- Reconsititution
- Format
- 신청
Chemical Information
Publications (1)
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Isotype

Human IgG1 kappa

Recommend Isotype Controls

Human IgG1 kappa, Isotype Control

Species Reactivity

Human

IC₅₀ & Target^[1]

GITR

All TNF Receptor Isoforms :

All NF-κB Isoforms :

In Vitro

FPA154 can potently exert antibody-dependent cell-mediated cytotoxicity against regulatory T cells that highly express GITR^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Gene ID

8784 [NCBI]

Accession

Q9Y5U5

Target

TNFRSF18/GITR/CD357

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Format

Product Image

신청

ELISA, FACS, Functional assay

Chemical Information

Synonyms

INBRX-110
Formulation

Please refer to the lot-specific COA for specific buffer information.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Journal Impact Factor

Appl Radiat Isot

[225Ac]Ac-Macropa-PEG4-FPA150 enables targeted alpha therapy of B7-H4-Expressing tumors. [Abstract]

2026 Jun 26:236:112778. PMID: 42365835

순도&문서

Inhibitory Antibodies User Guide (603 KB)

References

[1]. Susannah D. Barbee, et al. Abstract 613: Development of FPA154, a novel tetravalent anti-GITR antibody, for the treatment of solid tumors. Cancer Res 1 July 2017; 77 (13_Supplement): 613.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Other size

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Amount: USD 0.00

Biological Activity
- 제품 설명
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- IC₅₀ & Target
- In Vitro
- Gene ID
- Accession
- Target
- Conjugated
- Reconsititution
- Format
- 신청
Chemical Information
Publications (1)
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

FPA154

DPBS Buffer (1×)

Cytotoxicity LDH Assay Kit

PBS Buffer (1×)

Publications Citing Use of MedChemExpress (MCE) FPA154

All TNF Receptor Isoforms

All NF-κB Isoforms