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Cat. No.: HY-P1260

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FSLLRY-NH2

6 Cited Publications

고객리뷰

Based on 6 publication(s) in Google Scholar

FSLLRY-NH2 is a protease-activated receptor 2 (PAR2) inhibitor.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Purity: 99.89%
CAS No.: 245329-02-6
화학식: C₃₉H₆₀N₁₀O₈
분자량:796.96

보관:

Sealed storage, away from moisture and light.

Powder -80°C, 2 years , -20°C, 1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

FSLLRY-NH2 Chemical Structure

CAS No.: 245329-02-6

사이즈

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재고

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Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vivo
Chemical Information
Publications (6)
용액&용해도
- In Vitro
순도&문서
References
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

FSLLRY-NH2 is a protease-activated receptor 2 (PAR2) inhibitor^[1].

IC₅₀ & Target

PAR2

All Protease Activated Receptor (PAR) Isoforms :

In Vivo

Treatment with FSLLRY-NH2 (50 μg per rat administered intranasally at 1 hour postresuscitation) significantly improves neurological outcome and reduces the number of degenerating hippocampal neurons after ACA (asphyxial CA)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 245329-02-6
Appearance Solid
분자량 796.96
화학식 C₃₉H₆₀N₁₀O₈
Color White to off-white
Sequence

Phe-Ser-Leu-Leu-Arg-Tyr-NH2
Sequence Shortening

FSLLRY-NH2
선적

Room temperature in continental US; may vary elsewhere.

보관

Sealed storage, away from moisture and light

Powder	-80°C	2 years
	-20°C	1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Publications (6)

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Journal Impact Factor

J Immunother Cancer

Unveiling the mechanisms of CEBPD-orchestrated TAM polarization through RGS2/PAR2 pathway and its impact on ICB efficacy in clear cell renal cell carcinoma. [Abstract]

2025 Jul 13;13(7):e010898. PMID: 40659446
Brain Behav Immun

CD177 on neutrophils engages stress-related behavioral changes in male mice. [Abstract]

2024 Jun 12:120:403-412. PMID: 38871062
Biomolecules

PAR2 Participates in the Development of Cough Hypersensitivity in Guinea Pigs by Regulating TRPA1 Through PKC. [Abstract]

2025 Feb 1;15(2):208. PMID: 40001511
Cell Signal

Angiotensin II depends on hippo/YAP signaling to reprogram angiogenesis and promote liver fibrosis. [Abstract]

2024 Nov:123:111355. PMID: 39173854
BMC Musculoskelet Disord

Knockdown of PAR2 alleviates cancer-induced bone pain by inhibiting the activation of astrocytes and the ERK pathway. [Abstract]

2022 May 30;23(1):514. PMID: 35637468
Res Sq

2024 Sep 04.

용액&용해도

In Vitro:

DMSO : 100 mg/mL (125.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

1.2548 mL

6.2738 mL

12.5477 mL

5 mM

0.2510 mL

1.2548 mL

2.5095 mL

10 mM

0.1255 mL

0.6274 mL

1.2548 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Umut Ocak, et al. FSLLRY-NH2 Improves Neurological Outcome After Cardiac Arrest in Rats. Turk Neurosurg. 2020;30(2):244-251. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	1.2548 mL	6.2738 mL	12.5477 mL	31.3692 mL
	5 mM	0.2510 mL	1.2548 mL	2.5095 mL	6.2738 mL
	10 mM	0.1255 mL	0.6274 mL	1.2548 mL	3.1369 mL
	15 mM	0.0837 mL	0.4183 mL	0.8365 mL	2.0913 mL
	20 mM	0.0627 mL	0.3137 mL	0.6274 mL	1.5685 mL
	25 mM	0.0502 mL	0.2510 mL	0.5019 mL	1.2548 mL
	30 mM	0.0418 mL	0.2091 mL	0.4183 mL	1.0456 mL
	40 mM	0.0314 mL	0.1568 mL	0.3137 mL	0.7842 mL
	50 mM	0.0251 mL	0.1255 mL	0.2510 mL	0.6274 mL
	60 mM	0.0209 mL	0.1046 mL	0.2091 mL	0.5228 mL
	80 mM	0.0157 mL	0.0784 mL	0.1568 mL	0.3921 mL
	100 mM	0.0125 mL	0.0627 mL	0.1255 mL	0.3137 mL

Keywords

FSLLRY-NH2

6 Cited Publications

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vivo
Chemical Information
Publications (6)
용액&용해도
- In Vitro
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

FSLLRY-NH2

Peptide Library

Coagulation and Anti-coagulation Compound Library

Membrane Protein-targeted Compound Library

Membrane Receptor-targeted Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

High-Throughput Bioactive Compound Library

Lactylation Compound Library

GPCR/G Protein Compound Library

Peptide Compound Library

Publications Citing Use of MedChemExpress (MCE) FSLLRY-NH2

All Protease Activated Receptor (PAR) Isoforms

Biological Activity

Chemical Information

Publications (6)

용액&용해도

순도&문서

References

Help & FAQs

Complete Stock Solution Preparation Table

FSLLRY-NH2

Peptide Library

Coagulation and Anti-coagulation Compound Library

Membrane Protein-targeted Compound Library

Membrane Receptor-targeted Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

High-Throughput Bioactive Compound Library

Lactylation Compound Library

GPCR/G Protein Compound Library

Peptide Compound Library

Publications Citing Use of MedChemExpress (MCE) FSLLRY-NH2

All Protease Activated Receptor (PAR) Isoforms

Biological Activity

Chemical Information

Publications (6)

용액&용해도

순도&문서

References

Help & FAQs

Complete Stock Solution Preparation Table

FSLLRY-NH2 Related Classifications

HY-P1260 Related Classifications