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Cat. No.: HY-N20735

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Glucocamelinin

Name: Glucocamelinin
Brand: MedChemExpress
SKU: HY-N20735
Availability: PreOrder

(Synonyms: 10-(Methylsulfinyl)decylglucosinolate; GSL 10)

Glucocamelinin (GSL 10) is a sulfinyl glucosinolate identified from seeds of Camelina sativa and an upregulator of quinone reductase (NQO1). Glucocamelinin upregulates the activity of phase II detoxifying enzymes, exhibits selective cytotoxic activity against lung cancer cells, and possesses in vitro antioxidant activity. Glucocamelinin can be used in studies related to non-small cell lung cancer.

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CAS No.: 67884-10-0
화학식: C₁₈H₃₅NO₁₀S₃
분자량:521.67

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Glucocamelinin Chemical Structure

CAS No.: 67884-10-0

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

^[1]

NQO1

In Vitro

Glucocamelinin (1.25-5 μM; 24 h) shows no cytotoxicity at concentrations of 1.25 μM and 2.5 μM in Hepa1c1c7 mouse hepatocellular carcinoma cells, but reduces cell viability to approximately 70% of that in the control group at a concentration of 5 μM^[1].
Glucocamelinin (1.25-5 μM; 24 h) dose-dependently induces NQO1 activity in Hepa1c1c7 mouse hepatocellular carcinoma cells in vitro^[1].
Glucocamelinin (1.25-5 μM; 24 h) does not induce or inhibit the catalytic activity of CYP1A1 in Hepa1c1c7 mouse hepatocellular carcinoma cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

Hepa1c1c7 mouse hepatoma cells
Concentration:

1.25, 2.5, 5 μM
Incubation Time:

24 h
Result:

Showed no cytotoxicity relative to untreated controls at 1.25 μM and 2.5 μM.
Reduced cell survival to approximately 70% of the untreated control at 5 μM.

Chemical Information

CAS No. 67884-10-0
분자량 521.67
화학식 C₁₈H₃₅NO₁₀S₃
SMILES

CS(CCCCCCCCCC/C(S[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO)=N/OS(=O)(O)=O)=O
Synonyms

10-(Methylsulfinyl)decylglucosinolate; GSL 10
Structure Classification
- Saccharides
- Monosaccharides
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Das N, et al. Camelina sativa defatted seed meal contains both alkyl sulfinyl glucosinolates and quercetin that synergize bioactivity. Journal of agricultural and food chemistry. 2014 Aug 20;62(33):8385-91. [Content Brief]

[2]. Mark A, et al. Optimized analysis and quantification of glucosinolates from Camelina sativa seeds by reverse-phase liquid chromatography, Industrial Crops and Products, Volume 43, 2013, Pages 119-125, ISSN 0926-6690.

[3]. Čeh, et al. Glucosinulates content in camelina (Camelina sativa (L.) Crantz) seeds and oilcakes with regard to production location. Hop Bulletin. 2013. 20. 82-89.

[4]. A Schuster, et al. Glucosinolate content and composition as parameters of quality of Camelina seed, Industrial Crops and Products, Volume 7, Issues 2-3, 1998, Pages 297-302, ISSN 0926-6690.

[5]. Elena Ponzoni, et al. Comparative effects of glucosinolate-derived isothiocyanates from Camelina sativa seeds and sulforaphane on A549 lung cancer cells, Journal of Agriculture and Food Research, Volume 21, 2025, 101982, ISSN 2666-1543.

Calculators

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

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Glucocamelinin