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Cat. No.: HY-124461

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Guanicaine

Guanidine is a guanidine-containing compound with hypoglycemic activity, which can serve as a Drug Intermediate for synthesizing various guanidine-skeleton derivatives. Guanidine hydrochloride induces hypoglycemia in rabbits and causes symptoms identical to those of parathyroidectomy-induced tetany in rabbits. Guanicaine and its derivatives are applicable to diabetes-related research.

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CAS No.: 537-05-3
화학식: C₂₃H₂₆ClN₃O₃
분자량:427.92

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Guanicaine Chemical Structure

CAS No.: 537-05-3

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

In Vivo

Guanidine hydrochloride (administered via injection) reduces blood glucose levels in rabbits and induces tetany similar to that observed after parathyroidectomy^[1].
Guanidine produces monoguanidine derivative agmatine (HY-WAA0304) and its alkyl homologs that all exhibit hypoglycemic effects, among which pentamethylene monoguanidine shows the strongest hypoglycemic activity and the lowest toxicity^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Research Protocol for Metabolic Diseases

Chemical Information

CAS No. 537-05-3
분자량 427.92
화학식 C₂₃H₂₆ClN₃O₃
SMILES

CCOC(C=C1)=CC=C1/N=C(NC2=CC=C(C=C2)OC)/NC3=CC=C(C=C3)OC.Cl
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Braun C E. The chemistry of some suggested insulin substitutes. Journal of Chemical Education, 1931, 8: 2175.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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