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Cat. No.: HY-119574

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GW0791

GW0791 (Compound 3) is an RXRα agonist with an EC₅₀ of 5 nM. GW0791 can be used for cancer research.

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CAS No.: 503620-39-1
화학식: C₂₅H₃₀O₃
분자량:378.50

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

GW0791 Chemical Structure

CAS No.: 503620-39-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

GW0791 (Compound 3) is an RXRα agonist with an EC₅₀ of 5 nM. GW0791 can be used for cancer research^[1].

IC₅₀ & Target^[1]

RXR α

5 nM (EC₅₀)

All RAR/RXR Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
CV-1	EC₅₀	>10 μM Compound: 46a (enantiomer)	Effective concentration for Retinoic acid receptor alpha activity in CV-1 cells Effective concentration for Retinoic acid receptor alpha activity in CV-1 cells	[PMID: 15056000]
CV-1	EC₅₀	>790 nM Compound: 60	Effective concentration for Retinoic acid receptor alpha activity in CV-1 cells Effective concentration for Retinoic acid receptor alpha activity in CV-1 cells	[PMID: 15056000]

Chemical Information

CAS No. 503620-39-1
분자량 378.50
화학식 C₂₅H₃₀O₃
SMILES

OC(/C=C/C1=CC2=C(O1)CCCC2C3=CC=C(C(C)(CCC4(C)C)C)C4=C3)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Dong A, et al. A three-dimensional pharmacophore model for RXRα agonists. Journal of Molecular Structure. 2009 Feb 28;920(1-3):252-63.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
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GW0791

All RAR/RXR Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

GW0791 Related Classifications

HY-119574 Related Classifications