HIT-2
HIT-2 is an estrogen receptor alpha (ERα) inhibitor that can bind to the ERα ligand binding domain. HIT-2 forms stable interactions including hydrogen bonds, π-π stacking, and hydrophobic contacts to disrupt ERα-driven signaling. HIT-2 exhibits antineoplastic activity against breast cancer. HIT-2 can be used for the research of breast cancer.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C22H20N2O2S
- 분자량:376.47
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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ERα |
HIT-2 is predicted to fallunder Class IV oral toxicity, with an LD50 value of 830 mg/kg, indicating it is harmful if ingested but remains within an acceptable toxicity threshold for early[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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분자량 376.47
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화학식 C22H20N2O2S
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SMILES
CC(C=C1)=CC=C1C2=NC3=CC=CC=C3S[C@@H](C4=CC(N(O)O)=CC=C4)C2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HIT-2 Related Classifications
HY-181171 Related Classifications
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