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Human IgG1 lambda1, Isotype Control

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Based on 2 publication(s) in Google Scholar

Human IgG1 lambda1, Isotype Control, a human-derived antibody, is an isotype control for human IgG1λ1 antibody. Human IgG1 lambda1, Isotype Control can be used in the research of diabetes and pancreatic cancer.

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  • Purity: 99.64%
  • 분자량:141.84 kDa
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Human IgG1 lambda1, Isotype Control
  • Experimental Validation Results for Human IgG1 lambda1, Isotype Control
  • Experimental Validation Results for Human IgG1 lambda1, Isotype Control
  • Experimental Validation Results for Human IgG1 lambda1, Isotype Control
  • Human IgG1 lambda1, Isotype Control Chemical Structure
    Human IgG1 lambda1, Isotype Control Chemical Structure
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    Human IgG1 lambda1, Isotype Control purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Sep 30;16(1):8654. [Abstract]

    Customer Validation
     Pancreatic tumor samples from chow (n = 6 mice per group) and diabetic (n = 9 mice per group) KPC tumor-bearing mice treated with IgG (Human IgG1 lambda1, Isotype Control) (20 mg/kg; i.c.; once weekly for 2 weeks), bimagrumab (20 mg/kg; i.c.; once weekly for 2 weeks), or bimagrumab+metformin.

  • 1/16

    Human IgG1 lambda1, Isotype Control purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Sep 30;16(1):8654. [Abstract]

    Customer Validation
     Bar graph showing fasting blood glucose changes in diabetic tumor-bearing mice after treatment with 2 doses of IgG (Human IgG1 lambda1, Isotype Control) (20 mg/kg; i.c.; once weekly for 2 weeks), 2 doses of bimagrumab (20 mg/kg; i.c.; once weekly for 2 weeks) alone, or 2 doses of bimagrumab combined with 7 doses of metformin (n = 9 mice per group).

  • 1/16

    Human IgG1 lambda1, Isotype Control purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Sep 30;16(1):8654. [Abstract]

    Customer Validation
     Representative images and quantification of α-SMA staining (brown) in tumors from chow and diabetic KPC tumor-bearing mice treated with IgG (Human IgG1 lambda1, Isotype Control) (20 mg/kg; i.c.; once weekly for 2 weeks) or bimagrumab (20 mg/kg; i.c.; once weekly for 2 weeks) (n = 6 mice per group).

  • Human IgG1 lambda1, Isotype Control Chemical Structure
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  • Human IgG1 lambda1, Isotype Control
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