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Cat. No.: HY-105579

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Isonixin

Name: Isonixin
Brand: MedChemExpress
SKU: HY-105579
Availability: PreOrder

(Synonyms: Isonixine; Nixyn)

Isonixin (Isonixine) is a non-steroidal compound. Isonixin can be used for the research of pain and inflammation.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 57021-61-1
화학식: C₁₄H₁₄N₂O₂
분자량:242.27

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Isonixin Chemical Structure

CAS No.: 57021-61-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

Isonixin (Isonixine) is a non-steroidal compound. Isonixin can be used for the research of pain and inflammation^[1]^[2]^[3]^[4].

All COX Isoforms :

In Vivo

Isonixine potentiates hexobarbital sleep time, reduces motor activity, antagonizes cardiazol-induced convulsions, causes hyperthermia, and inhibits tremorine-induced trembling in mice^[1].
Isonixine (p.o.) showes a 3.15 h half-life of absorption and rapidly absorbs in a gastro-intestinal tract^[2].
Isonixine (i.v., intragastrically and intraduodenally) mainly excrets via urine, and isonixine can be eliminated by urine within 50 hours^[3].
Isonixine (2000 mg/kg; p.o. once daily for 6 months) presents some mild toxic effects and induces no gastrointestinal lesion in male rabbits and rats^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 57021-61-1
분자량 242.27
화학식 C₁₄H₁₄N₂O₂
SMILES

O=C(C1=CC=CNC1=O)NC2=C(C=CC=C2C)C
Synonyms

Isonixine; Nixyn
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mitjavila MT, Martorell M. Algunos efectos de la isonixina sobre el sistema nervioso central [Various effects of isonixine on the central nervous system]. Arch Farmacol Toxicol. 1979 Dec;5(3):183-4. [Content Brief]

[2]. Carrera G, et al. Studies of absorption, distribution and excretion of 2,6-xylidide of 2-pyridone-3-carboxylic acid (isonixine). Arzneimittelforschung. 1979;29(9):1401-4. [Content Brief]

[3]. Carrera G, et al. Etude pharmacocinétique de l'isonixine [Pharmacokinetic study of isonixine]. Arch Farmacol Toxicol. 1978 Apr;4(1):111-2. [Content Brief]

[4]. Mitjavila MT, et al. Toxicological investigations of isonixine. Arzneimittelforschung. 1977 Jul;27(7):1460-4. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
- In Vivo
Chemical Information
순도&문서
References

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Isonixin

All COX Isoforms