JGB1741 (Standard)

(Synonyms: ILS-JGB-1741 (Standard))

JGB1741 (Standard) is the analytical standard of JGB1741 (HY-111329). This product is intended for research and analytical applications. JGB1741 (ILS-JGB-1741) is a potent and specific SIRT1 activity inhibitor with an IC50 of ~15 μM. JGB1741 is a weak SIRT2 and SIRT3 inhibitor with an all IC50>100 μM. JGB1741 increases the acetylated p53 levels leading to p53-mediated apoptosis with modulation of Bax/Bcl2 ratio, cytochrome c release and PARP cleavage. JGB1741 has the potential for breast cancer research.

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  • CAS No.: 1256375-38-8
  • 화학식: C27H24N2O2S
  • 분자량:440.56
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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Minimum order quantity
100 mg

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