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United States

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Cat. No.: HY-123410

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KM-233

KM-233 is a classical cannabinoid with good blood brain barrier penetration. KM-233 possesses a selective affinity for the CB2 receptors relative to THC. KM-233 is effective at reducing U87 glioma tumor burden, and can be used for glioma research.

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CAS No.: 628263-22-9
화학식: C₂₅H₃₀O₂
분자량:362.50

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

KM-233 Chemical Structure

CAS No.: 628263-22-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All Cannabinoid Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
LN-229	EC₅₀	2.63 μM Compound: 2	Cytotoxicity against human LN229 cells assessed as cell death after 18 hrs Cytotoxicity against human LN229 cells assessed as cell death after 18 hrs	[PMID: 18524604]
T98G	EC₅₀	4.68 μM Compound: 2	Cytotoxicity against human T98G cells assessed as cell death after 18 hrs Cytotoxicity against human T98G cells assessed as cell death after 18 hrs	[PMID: 18524604]
U-87MG ATCC	EC₅₀	3.08 μM Compound: 2	Cytotoxicity against human U87 cells by side flank model relative to control Cytotoxicity against human U87 cells by side flank model relative to control	[PMID: 18524604]

Chemical Information

CAS No. 628263-22-9
분자량 362.50
화학식 C₂₅H₃₀O₂
SMILES

OC1=CC(C(C2=CC=CC=C2)(C)C)=CC3=C1[C@]4([H])CC(C)=CC[C@]4(C(C)(O3)C)[H]
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Duntsch C, et al. Safety and efficacy of a novel cannabinoid chemotherapeutic, KM-233, for the treatment of high-grade glioma. J Neurooncol. 2006 Apr;77(2):143-52. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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KM-233

High-Throughput Bioactive Compound Library

All Cannabinoid Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

KM-233 Related Classifications

HY-123410 Related Classifications