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Cat. No.: HY-117644

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L-749329

Name: L-749329
Brand: MedChemExpress
SKU: HY-117644
Availability: PreOrder

(Synonyms: (Rac)-L-754142)

L-749329 ((Rac)-L-754142) is an ET_A and ET_B receptor antagonist, with K_is of 0.062 nM and 2.25 nM for ET_A and ET_B respectively. L-749329 inhibits ET-1-stimulated signaling.

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CAS No.: 159590-37-1
화학식: C₂₈H₂₉NO₈S
분자량:539.60

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

L-749329 Chemical Structure

CAS No.: 159590-37-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

L-749329 ((Rac)-L-754142) is an ET_A and ET_B receptor antagonist, with K_is of 0.062 nM and 2.25 nM for ET_A and ET_B respectively. L-749329 inhibits ET-1-stimulated signaling^[1].

All Endothelin Receptor Isoforms :

ET_A
ET_B

Chemical Information

CAS No. 159590-37-1
분자량 539.60
화학식 C₂₈H₂₉NO₈S
SMILES

O=C(C1=CC=C(C(CCC)=C1)OC(C2=CC=C3OCOC3=C2)C(NS(=O)(C4=CC=C(C(C)C)C=C4)=O)=O)O
Synonyms

(Rac)-L-754142
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Huckle WR, et al. Effects of L-749,329, an ET(A)/ET(B) endothelin receptor antagonist, in a porcine coronary artery injury model of vascular restenosis. Circulation. 2001 Apr 10;103(14):1899-905. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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L-749329

All Endothelin Receptor Isoforms

Biological Activity

제품 설명

Chemical Information

순도&문서

References

Calculators

Help & FAQs

L-749329 Related Classifications

HY-117644 Related Classifications

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