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Cat. No.: HY-126497

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LC-PEG8-SPDP

LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1252257-56-9
화학식: C₃₁H₄₉N₃O₁₃S₂
분자량:735.86

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (261 KB)

LC-PEG8-SPDP Chemical Structure

CAS No.: 1252257-56-9

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Use of MCE Products

One-stop CDMO Service

One-Stop Platform：From Independent R&D to Pilot-Scale Production

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
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Biological Activity

제품 설명

LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs)^[1].

IC₅₀ & Target^[1]

Disulfide Cleavable Linker

Cleavable Linker

All ADC Linkers Isoforms :

Chemical Information

CAS No. 1252257-56-9
분자량 735.86
화학식 C₃₁H₄₉N₃O₁₃S₂
SMILES

O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCSSC2=NC=CC=C2)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (261 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhao RY, et al. Synthesis and evaluation of hydrophilic linkers for antibody-maytansinoid conjugates. J Med Chem. 2011 May 26;54(10):3606-23. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
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LC-PEG8-SPDP

SPDP-PEG4-NHS ester

Bis-PEG9-NHS ester

PEG4-SPDP

Thiol-PEG8-acid

SPDP-PEG6-NHS ester

m-PEG4-Amine

NH2-PEG3-C2-Boc

m-PEG20000-azide

mPEG20000-N3

Lipoamido-PEG8-acid

All ADC Linkers Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Bioz

LC-PEG8-SPDP

SPDP-PEG4-NHS ester

Bis-PEG9-NHS ester

PEG4-SPDP

Thiol-PEG8-acid

SPDP-PEG6-NHS ester

m-PEG4-Amine

NH2-PEG3-C2-Boc

m-PEG20000-azide

mPEG20000-N3

Lipoamido-PEG8-acid

All ADC Linkers Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

LC-PEG8-SPDP Related Classifications

HY-126497 Related Classifications

Bioz