LDC0496
LDC0496 is a potent and selective EGFR inhibitor. LDC0496 possesses intense inhibitory potency toward EGFR and Her2 exon20 insertion mutations, as well as selectivity over wild type EGFR and within the kinome.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 2411874-83-2
- 화학식: C32H35N5O3
- 분자량:537.65
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
All EGFR Isoforms
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Biological Activity
IC50: 0.152 ± 0.011 μM in Ba/F3 (EGFR-insNPH), 0.162 ± 0.010 μM in Ba/F3 (Her2-insYVMA), 2.660 ± 0.129 in A431[1]
Chemical Information
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CAS No. 2411874-83-2
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분자량 537.65
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화학식 C32H35N5O3
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SMILES
CC(C=CC(C1=C(NC2=NC=C(C=C21)C(OC(C)C)=O)C3=CC=C(C=C3)N4CCN(CC4)C)=C5)=C5NC(C=C)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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