Liquid Paraffin
Based on 1 publication(s) in Google Scholar
Liquid Paraffin is a petroleum-derived mixture of saturated hydrocarbons and an orally active fecal lubricant. Liquid Paraffin is widely used in studies of constipation and fecal incontinence in children through its lubricating effect and the osmotic effect generated by its conversion to hydroxy fatty acids. Liquid Paraffin has high safety, is non-carcinogenic, and does not affect fat-soluble vitamin levels with long-term use. Liquid Paraffin does not cause abdominal pain or electrolyte disorders, but may lead to lipoid pneumonia and granulomas caused by rectal administration. Liquid Paraffin can also be used as a phase change material for thermal energy storage, or combined with nanoparticles to form a protective boundary film to reduce mechanical wear.
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- CAS No.: 8012-95-1
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보관:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Publications Citing Use of MedChemExpress (MCE) Liquid Paraffin
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
40 μM
Compound: Delphinidin
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Antiproliferative activity against human HL60 cells after 48 hrs by MTS assay
Antiproliferative activity against human HL60 cells after 48 hrs by MTS assay
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[PMID: 20801663] |
| HL-60 | IC50 |
80 μM
Compound: Delphinidin
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Antiproliferative activity against human HL60 cells after 24 hrs by MTS assay
Antiproliferative activity against human HL60 cells after 24 hrs by MTS assay
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[PMID: 20801663] |
When Liquid Paraffin is compounded with EHA-TiO2 nanoparticles, its load-carrying capacity, anti-wear property and friction-reducing property are all improved; among them, the maximum non-seizure load of the pure base oil is 400 N[2].
Liquid Paraffin can be used as a base raw material for lubricating oils, with properties including low sulfur content, undetectable acidity, and specific viscosity values at 50°C and 100°C[3].
Liquid paraffin (containing 4 wt.% GNPs) remains stable for at least 1.5 h after preparation, but its long-term stability is reduced compared with suspensions containing smaller-sized carbon nanomaterials (visible precipitation occurs 1 day after preparation)[5].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Liquid Paraffin (i.e., pharmaceutical liquid paraffin formulation) shows no carcinogenic activity in dogs following dietary intake during subchronic study periods[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 8012-95-1
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Appearance Liquid (Density: 0.875-0.905 g/cm3)
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Color Colorless to light yellow
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SMILES
[Liquid Paraffin]
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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ACS Nano
Topology Outweighs Stiffness: Self-Reinforced Cell Mechanotransduction via Multiaxial Curvature Engineering of Ultrasoft Hydrogels. [Abstract]2026 Mar 10;20(9):7679-7692. PMID: 41733433
순도&문서
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Data Sheet (269 KB)
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SDS (418 KB)
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- Italian - IT (418 KB)
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- Portuguese - PT (418 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Liquid Paraffin Related Classifications
HY-154636 Related Classifications
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