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Cat. No.: HY-N8453

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Macranthoin G

(Synonyms: Methyl 3,5-dicaffeoyl quinic acid)

Macranthoin G is an inhibitor of p38 MAPK. Macranthoin G protects the cytotoxicity induced by Aβ or hydrogen peroxide in neuronal cells by downregulating p38 MAPK. Macranthoin G can used in study Alzheimer’s Disease.

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CAS No.: 159934-13-1
화학식: C₂₆H₂₆O₁₂
분자량:530.48

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Macranthoin G Chemical Structure

CAS No.: 159934-13-1

사이즈

가격

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수량

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All p38 MAPK Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
BV-2	IC₅₀	9.04 μM Compound: 8	Anti-neuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 10 mins by Griess assay relative to control Anti-neuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 10 mins by Griess assay relative to control	[PMID: 23462643]
HeLa	IC₅₀	7.59 μM Compound: RLE12	Inhibition of HDAC in human HeLa cells using Boc-Lys(AC)-AMC as substrate after 24 to 48 hrs by spectrofluorometry Inhibition of HDAC in human HeLa cells using Boc-Lys(AC)-AMC as substrate after 24 to 48 hrs by spectrofluorometry	[PMID: 26996372]
RAW264.7	IC₅₀	42.87 μM Compound: 8	Anti-neuroinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production Anti-neuroinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production	[PMID: 23462643]

Chemical Information

CAS No. 159934-13-1
분자량 530.48
화학식 C₂₆H₂₆O₁₂
SMILES

O=C(OC)[C@@](C1)(O)C[C@@H](OC(/C=C/C2=CC(O)=C(O)C=C2)=O)[C@H](O)[C@@H]1OC(/C=C/C3=CC(O)=C(O)C=C3)=O
Synonyms

Methyl 3,5-dicaffeoyl quinic acid
Structure Classification
- Phenols
- Polyphenols
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lee JK, et al. Recent Advances in the Inhibition of p38 MAPK as a Potential Strategy for the Treatment of Alzheimer's Disease. Molecules. 2017 Aug 2;22(8):1287. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
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Macranthoin G

All p38 MAPK Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Macranthoin G Related Classifications

HY-N8453 Related Classifications