Mocertatug
Based on 1 Customer Validation
Mocertatug (GSK5733584 antibody) is a humanized IgG1κ antibody targeting B7-H4/VTCN1. Mocertatug can be used to construct ADCs, such as Mocertatug Rezetecan (HY-185280).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 98%
- CAS No.: 3042847-92-4
- 분자량:145.246 kDa
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Human IgG1 kappa
Human
B7-H4/VTCN1
Mocertatug Rezetecan consists of Mocertatug and the topoisomerase I (TOPO1) inhibitor Rezetecán (HY-147408), and induces cell cycle S-phase arrest, cytotoxicity and bystander killing effect[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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IgG1-kappa
ELISA, FACS, Functional assay
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Loaded Mocertatug on ProA biosensor, can bind B7-H4 Protein, Human (HEK293, His, HY-P74395) with an affinity constant of 1.401E-07 M as determined in BLI assay.
Chemical Information
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CAS No. 3042847-92-4
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Appearance Liquid
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분자량 145.246 kDa
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Color Colorless to light yellow
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SMILES
N/A
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Synonyms
GSK5733584 antibody; HS-20089 antibody; hu2F7
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선적
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
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Data Sheet (257 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)