MS6178
MS6178 is a MS5105-based CFTR deubiquitinase-targeted chimera (DUBTAC) that recruits OTUB1 to stabilize ΔF508-CFTR mutant protein in a concentration- and time-dependent manner, with an OTUB1-dependent effect and no impact on CFTR mRNA level. MS6178 can be used for the research of cancer.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 3060520-53-5
- 화학식: C47H53F2N7O7S
- 분자량:898.03
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
MS6178 (0.5-10 µM; 0-24 h) effectively stabilizes the ΔF508-CFTR mutant protein in CFBE41o-4.7 ΔF508-CFTR cells in a concentration-, time-, OTUB1-, and CFTR-dependent manner (30-fold increase at 10 μM for 24 h)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3060520-53-5
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분자량 898.03
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화학식 C47H53F2N7O7S
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SMILES
O=C(NC1=NC(C2=CC=CC(C(NCCCCCCC(NCCC3=CC=C(N4CCN(C(/C=C/CN(C)C)=O)CC4=O)S3)=O)=O)=C2)=C(C)C=C1)C5(CC5)C6=CC7=C(OC(F)(F)O7)C=C6
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MS6178 Related Classifications
HY-185122 Related Classifications
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