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Cat. No.: HY-162872

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NBI-35965

1 Cited Publications

고객리뷰

Based on 1 publication(s) in Google Scholar

NBI-35965 is an antagonist of corticotropin-releasing factor receptor 1 (CRF-R1). NBI-35965 can be used in nervous system related research.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 268546-19-6
화학식: C₂₁H₂₂Cl₂N₄
분자량:401.33

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

NBI-35965 Chemical Structure

CAS No.: 268546-19-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
Publications (1)
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

NBI-35965 is an antagonist of corticotropin-releasing factor receptor 1 (CRF-R1). NBI-35965 can be used in nervous system related research^[1].

IC₅₀ & Target

CRFR1

All CRFR Isoforms :

CRFR1
CRFR2

Chemical Information

CAS No. 268546-19-6
분자량 401.33
화학식 C₂₁H₂₂Cl₂N₄
SMILES

CC[C@H]1CN2N=C(C3=C(C=C(C=C3)Cl)Cl)C4=NC(C)=CC(N1CC5CC5)=C42
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Adv Sci (Weinh)

PVNCRF Neurons Regulate Migraine-Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons. [Abstract]

2026 Feb 28:e20530. PMID: 41762709

순도&문서

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Li C, et al. CRF-5-HT interactions in the dorsal raphe nucleus and motivation for stress-induced opioid reinstatement. Psychopharmacology (Berl). 2021 Jan;238(1):29-40. [Content Brief]

Calculators

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Mass Mass

Concentration Concentration

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

NBI-35965

1 Cited Publications

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Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
Publications (1)
순도&문서
References

상품명:
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NBI-35965

Publications Citing Use of MedChemExpress (MCE) NBI-35965

All CRFR Isoforms

Biological Activity

Chemical Information

Publications (1)

순도&문서

References

Calculators

Help & FAQs

NBI-35965 Related Classifications

HY-162872 Related Classifications