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Cat. No.: HY-117598

OXFBD03

OXFBD03 serves as an inhibitor of the BRD4(1) protein, which belongs to the bromodomain and extra terminal domain bromodomain family.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

CAS No.: 1429129-71-4

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

OXFBD03 serves as an inhibitor of the BRD4(1) protein, which belongs to the bromodomain and extra terminal domain bromodomain family.

All Epigenetic Reader Domain Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	>10 μM Compound: 9	Cytotoxicity against human A549 cells after 72 hrs by MTS assay Cytotoxicity against human A549 cells after 72 hrs by MTS assay	[PMID: 23517011]
HeLa	IC₅₀	>100 μM Compound: 9	Cytotoxicity against human HeLa cells after 24 hrs by WST-1 assay Cytotoxicity against human HeLa cells after 24 hrs by WST-1 assay	[PMID: 23517011]
MV4-11	IC₅₀	0.616 μM Compound: 9	Cytotoxicity against human MV4-11 cells after 72 hrs by MTS assay Cytotoxicity against human MV4-11 cells after 72 hrs by MTS assay	[PMID: 23517011]
NCI-H1975	IC₅₀	>10 μM Compound: 9	Cytotoxicity against human NCI-H1975 cells after 72 hrs by MTS assay Cytotoxicity against human NCI-H1975 cells after 72 hrs by MTS assay	[PMID: 23517011]
U2OS	IC₅₀	>100 μM Compound: 9	Cytotoxicity against human U2OS cells after 24 hrs by WST-1 assay Cytotoxicity against human U2OS cells after 24 hrs by WST-1 assay	[PMID: 23517011]

CAS No. 1429129-71-4
분자량 337.37
화학식 C₂₀H₁₉NO₄
SMILES

OC(C1=CC=CC=C1)C2=CC(C3=C(C)ON=C3C)=CC(OC(C)=O)=C2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.