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Cat. No.: HY-P10350

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PapRIV

3 Cited Publications

고객리뷰

Based on 3 publication(s) in Google Scholar

PapRIV is an agonist of BV-2 microglial cells, capable of activating microglial cells through an NF-κB-dependent pathway. PapRIV induces the expression of pro-inflammatory cytokines such as IL-6 and TNFα and increases the production of reactive oxygen species (ROS). PapRIV can cross the blood-brain barrier.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₃₈H₅₃N₉O₁₃
분자량:843.88

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

PapRIV Chemical Structure

사이즈

가격

재고

수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All NF-κB Isoforms :

Chemical Information

분자량 843.88
화학식 C₃₈H₅₃N₉O₁₃
Sequence

Ser-Asp-Leu-Pro-Phe-Glu-His
Sequence Shortening

SDLPFEH
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (3)

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CNS Neurosci Ther

Cycloastragenol Derivatives Improve Tyrosine Metabolism, Regulate TLR4/NF-κB/TERT Signaling Pathways, and Inhibit MPTP Induced Neuroinflammation and PD Symptoms. [Abstract]

2026 Feb;32(2):e70787. PMID: 41670296
CNS Neurosci Ther

Neuroprotective Effects of Transcranial Pulsed Current Stimulation: Modulation of Microglial Polarization in Traumatic Brain Injury. [Abstract]

2025 Sep;31(9):e70606. PMID: 40916543
Cardiovasc Toxicol

Chronic Anatabine Administration Attenuates Cardiovascular Activity by Targeting NF-κB/NLRP3/Caspase-1-Dependent Pyroptosis and Oxidative Stress in Paraventricular Nucleus of Hypertensive Rat. [Abstract]

2025 Sep;25(9):1352-1368. PMID: 40690148

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (258 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Janssens Y, et al. PapRIV, a BV-2 microglial cell activating quorum sensing peptide. Sci Rep. 2021 May 21;11(1):10723. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
Publications (3)
순도&문서
References

상품명:
Cat. No.:
수량:
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PapRIV

Publications Citing Use of MedChemExpress (MCE) PapRIV

All NF-κB Isoforms