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Cat. No.: HY-162438

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PHD2-IN-2

PHD2-IN-2 (Compound 12) is a PHD2 inhibitor, with an IC₅₀ of 34.3 nM. PHD2-IN-2 has high erythropoietin (EPO) inducing activity, with an EC₅₀ of 6.79 μM. PHD2-IN-2 can be used for the research of anemia, ischemia, and hypoxia.

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CAS No.: 3033029-60-3
화학식: C₁₉H₁₈N₄O₄
분자량:366.37

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

PHD2-IN-2 Chemical Structure

CAS No.: 3033029-60-3

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All HIF/HIF Prolyl-Hydroxylase Isoforms :

In Vivo

PHD2-IN-2 (3 mg/kg, daily for 14 days) increases the level of EPO in SD rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3033029-60-3
분자량 366.37
화학식 C₁₉H₁₈N₄O₄
SMILES

OC1=C(C(NCC(O)=O)=O)C2=NC=NN2C(C(CC3)CC4=C3C=CC=C4)=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Tang HT, et al. Prolyl hydroxylase inhibitor and use thereof. WO2024061172A1.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- In Vivo
Chemical Information
순도&문서
References

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PHD2-IN-2

All HIF/HIF Prolyl-Hydroxylase Isoforms