PKZ18

PKZ18 is an antibiotic and inhibits bacterial growth, with MIC values of 32-64 μg/mL against most Gram-positive bacteria. PKZ18 inhibits in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria and directly reduces T-box transcriptional read-through of the associated genes. PKZ18 prevents the codon-anticodon reading required for tRNA binding and is refractory to resistance.

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  • CAS No.: 849658-87-3
  • 화학식: C22H26N2O3S
  • 분자량:398.52
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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