Cathepsin E
Cathepsin E (CTSE) is a non-lysosomal aspartic protease that exists predominantly as a disulfide-linked homodimer, setting it apart from the monomeric lysosomal Cathepsin D. The enzyme resides mainly in endosomal compartments of gastric mucosal cells, immune cells, and cells of the gastrointestinal tract and lung, where it contributes to antigen processing for MHC class II presentation. CTSE expression is inducible during inflammation, and elevated levels have been reported in various carcinomas. Mouse knockout studies point to roles in immune responses and in the stomach epithelium rather than in bulk protein turnover, a housekeeping function dominated by Cathepsin D.
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Cathepsin E Recombinant Proteins (3)
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Inhibitors & Agonists (9)
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- 화학식: Human
- 분자량: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
