Pseudolaric Acid C
Based on 1 Customer Validation
Pseudolaric C is a diterpenoid isolated from the root bark of Pseudolarix amabilis, has antifungal activity.
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- Purity: 99.74%
- CAS No.: 82601-41-0
- 화학식: C21H26O7
- 분자량:390.43
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Bioactive Compound Library Max
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MCE Bioactive Compound Library
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Natural Product Library Plus
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Natural Product and Natural Product-Like Compound Library
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Bioactive Compound Library
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RO5 Drug-like Natural Product Library
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High-Throughput Bioactive Compound Library
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High-Throughput Natural Product Library
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Diarrhea-Related Traditional Chinese Medicine Active Compound Library
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Natural Product Diversity Scaffold Library
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Mass Spectrometry Natural Product Library
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
>10 μM
Compound: 3, pseudolaric acid C
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Antiproliferative activity against human HL60 cells by SRB assay
Antiproliferative activity against human HL60 cells by SRB assay
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[PMID: 18078313] |
| HMEC-1 | IC50 |
>10 μM
Compound: 3, pseudolaric acid C
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Antiproliferative activity against HMEC1 cells by SRB assay
Antiproliferative activity against HMEC1 cells by SRB assay
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[PMID: 18078313] |
Chemical Information
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CAS No. 82601-41-0
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Appearance Solid
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분자량 390.43
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화학식 C21H26O7
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Color White to off-white
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SMILES
O=C(C1=CC[C@@]([C@@](CC1)(O)[C@]2([H])[C@@](C)(/C=C/C=C(C(O)=O)\C)O3)(CC2)C3=O)OC
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 100 mg/mL (256.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (6.40 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
순도&문서
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5613 mL | 12.8064 mL | 25.6128 mL | 64.0320 mL |
| 5 mM | 0.5123 mL | 2.5613 mL | 5.1226 mL | 12.8064 mL | |
| 10 mM | 0.2561 mL | 1.2806 mL | 2.5613 mL | 6.4032 mL | |
| 15 mM | 0.1708 mL | 0.8538 mL | 1.7075 mL | 4.2688 mL | |
| 20 mM | 0.1281 mL | 0.6403 mL | 1.2806 mL | 3.2016 mL | |
| 25 mM | 0.1025 mL | 0.5123 mL | 1.0245 mL | 2.5613 mL | |
| 30 mM | 0.0854 mL | 0.4269 mL | 0.8538 mL | 2.1344 mL | |
| 40 mM | 0.0640 mL | 0.3202 mL | 0.6403 mL | 1.6008 mL | |
| 50 mM | 0.0512 mL | 0.2561 mL | 0.5123 mL | 1.2806 mL | |
| 60 mM | 0.0427 mL | 0.2134 mL | 0.4269 mL | 1.0672 mL | |
| 80 mM | 0.0320 mL | 0.1601 mL | 0.3202 mL | 0.8004 mL | |
| 100 mM | 0.0256 mL | 0.1281 mL | 0.2561 mL | 0.6403 mL |
Pseudolaric Acid C Related Classifications
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