(rel)-MK 287
(rel)-MK 287 ((rel)-L-680573) is a relative configuration of MK 287. MK 287 is a potent, selective and orally active antagonist of platelet-activating factor receptor (PAFR). MK 287 can inhibit [3H]C18-PAF binding to human platelet, polymorphonuclear leukocyte (PMN) and lung membranes with K1 values of 6.1, 3.2, and 5.49 nM, respectively. MK 287 can inhibit PAF-induced aggregation of platelets in plasma or gel-filtered platelets and elastase release from PMNs with ED50 values of 56, 1.5 and 4.4 nM. MK 287 can be used for the research of cardiovascular disease, such as thrombosis.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 143445-03-8
- 화학식: C25H34O9S
- 분자량:510.60
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Biological Activity
제품 설명
Chemical Information
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CAS No. 143445-03-8
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분자량 510.60
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화학식 C25H34O9S
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SMILES
O=S(CCO)(C1=CC([C@H]2O[C@@H](CC2)C3=CC(OC)=C(C(OC)=C3)OC)=CC(OC)=C1OCCC)=O
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Synonyms
(rel)-L-680573
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(rel)-MK 287 Related Classifications
HY-106899A Related Classifications
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