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Cat. No.: HY-103022R

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Repotrectinib (Standard)

Name: Repotrectinib (Standard)
Brand: MedChemExpress
SKU: HY-103022R
Availability: PreOrder

(Synonyms: TPX-0005 (Standard))

Repotrectinib (Standard) is the analytical standard of Repotrectinib (HY-103022). This product is intended for research and analytical applications. Repotrectinib (TPX-0005) is a potent ROS1 (IC₅₀=0.07 nM) and TRK (IC₅₀=0.83/0.05/0.1 nM for TRKA/B/C) inhibitor. Repotrectinib potently inhibits WT ALK (IC₅₀=1.01 nM). Repotrectinib has anti-cancer activity.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1802220-02-5
화학식: C₁₈H₁₈FN₅O₂
분자량:355.37

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Repotrectinib (Standard) Chemical Structure

CAS No.: 1802220-02-5

사이즈

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Product Information

Information

신청

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1802220-02-5
분자량 355.37
화학식 C₁₈H₁₈FN₅O₂
SMILES

O=C1NC[C@H](C)OC2=CC=C(F)C=C2[C@@H](C)NC3=NC4=C1C=NN4C=C3
Synonyms

TPX-0005 (Standard)
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Dayong Zhai, et al. Abstract 2132: The novel, rationally-designed, ALK/SRC inhibitor TPX-0005 overcomes multiple acquired resistance mechanisms to current ALK inhibitors. Cancer Research. July 2016

[2]. Karachaliou N, et al. Common Co-activation of AXL and CDCP1 in EGFR-mutation-positive Non-smallcell Lung Cancer Associated With Poor Prognosis. EBioMedicine. 2018 Mar;29:112-127. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Chemical Information
순도&문서

상품명:
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수량:
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Repotrectinib (Standard)

Repotrectinib

Alectinib

Brigatinib

AZD-3463

Lorlatinib

Ceritinib

Alectinib (Standard)

Entrectinib

GSK1838705A

LDN193189 dihydrochloride

NVP-TAE 684

Crizotinib

Product Information

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Bioz

Repotrectinib (Standard)

Repotrectinib

Alectinib

Brigatinib

AZD-3463

Lorlatinib

Ceritinib

Alectinib (Standard)

Entrectinib

GSK1838705A

LDN193189 dihydrochloride

NVP-TAE 684

Crizotinib

Product Information

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Repotrectinib (Standard) Related Classifications

HY-103022R Related Classifications

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