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Cat. No.: HY-158790A

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(S)-HTS-3

(S)-HTS-3 is a Lysophosphatidylcholine acyltransferase 3 (LPCAT3/MBOAT5) inhibitor with a human IC₅₀ of 4.1 μM. (S)-HTS-3 inhibits the acyltransferase activity of LPCAT3. (S)-HTS-3 modestly reduces incorporation of deuterated arachidonic acid into C20:4 phosphatidylserine in myeloid leukemia cells.

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CAS No.: 2771208-82-1
화학식: C₁₇H₁₈F₂N₂O
분자량:304.33

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

(S)-HTS-3 Chemical Structure

CAS No.: 2771208-82-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

In Vitro

(S)-HTS-3 weakly inhibits recombinant human LPCAT3 in membrane lysates from HEK293T cells with an IC₅₀ of 4.1 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2771208-82-1
분자량 304.33
화학식 C₁₇H₁₈F₂N₂O
SMILES

O=C(C1=CC(F)=CC(F)=C1)NC[C@H](C2=CC=CC=C2)N(C)C
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Reed A, et al. LPCAT3 Inhibitors Remodel the Polyunsaturated Phospholipid Content of Human Cells and Protect from Ferroptosis. ACS chemical biology. 2022 Jun 17;17(6):1607-1618. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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