Sootepin D
Sootepin D (compound 6), a triterpene from the apical bud of Gardenia sootepensis, inhibits TNF-α-induced NF-κB activity with an IC50 of 8.3μM. Sootepin D has anti-inflammatory activity.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 1154518-97-4
- 화학식: C31H48O4
- 분자량:484.71
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
NF-κB |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BT-474 | IC50 |
>10 μg/mL
Compound: 4
|
Cytotoxicity against human BT474 cells after 3 days by MTT assay
Cytotoxicity against human BT474 cells after 3 days by MTT assay
|
[PMID: 19456120] |
| HepG2 | IC50 |
>10 μg/mL
Compound: 4
|
Cytotoxicity against human HepG2 cells after 3 days by MTT assay
Cytotoxicity against human HepG2 cells after 3 days by MTT assay
|
[PMID: 19456120] |
| SW-620 | IC50 |
>10 μg/mL
Compound: 4
|
Cytotoxicity against human SW620 cells after 3 days by MTT assay
Cytotoxicity against human SW620 cells after 3 days by MTT assay
|
[PMID: 19456120] |
Chemical Information
-
CAS No. 1154518-97-4
-
분자량 484.71
-
화학식 C31H48O4
-
SMILES
COC(CC[C@@]12[C@]3([C@](CC[C@H]2C(CO)=C)([H])[C@]4([C@@](C)([C@]([C@H](C)CC/C=C(C)/C=O)([H])CC4)CC3)C)C1)=O
-
Structure Classification
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)