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Cat. No.: HY-161045

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T-1-DOCA

T-1-DOCA ia a EGFR inhibitor, with the IC₅₀ of 56.94 and 269.01?nM for EGFR^WT and EGFR^T790M, respectively. T-1-DOCA can induces cell apoptosis of HCT-116 cells.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₁₅H₁₃Cl₂N₅O₃
분자량:382.20

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

T-1-DOCA Chemical Structure

사이즈

가격

재고

수량

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Use of MCE Products

Antibody-Drug Conjugates

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Biological Activity

제품 설명

T-1-DOCA ia a EGFR inhibitor, with the IC₅₀ of 56.94 and 269.01?nM for EGFR^WT and EGFR^T790M, respectively. T-1-DOCA can induces cell apoptosis of HCT-116 cells^[1].

All EGFR Isoforms :

Chemical Information

분자량 382.20
화학식 C₁₅H₁₃Cl₂N₅O₃
SMILES

O=C(C(N(C)C=N1)=C1N2C)N(CC(NC3=C(Cl)C=CC=C3Cl)=O)C2=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Eissa IH, et al. Computer-Assisted Drug Discovery of a Novel Theobromine Derivative as an EGFR Protein-Targeted Apoptosis Inducer. Evol Bioinform Online. 2023;19:11769343231217916. Published 2023 Dec 1. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
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T-1-DOCA

All EGFR Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

T-1-DOCA Related Classifications

HY-161045 Related Classifications